Cirrhosis and liver transplantation in patients co-infected with HIV and hepatitis B or C: an observational cohort study.

TitleCirrhosis and liver transplantation in patients co-infected with HIV and hepatitis B or C: an observational cohort study.
Publication TypeJournal Article
Year of Publication2017
AuthorsWarren-Gash C, Childs K, Thornton A, Bhagani S, Demma S, Srivastava A, Leen C, Agarwal K, Rodger A and Sabin C
Corporate AuthorsJoint UK CHIC and liver transplant advisory group
JournalInfection
Volume45
Issue2
Pagination215-220
Date Published2017 Apr
ISSN1439-0973
KeywordsAdult, Coinfection, Female, Hepatitis B, Chronic, Hepatitis C, Chronic, HIV Infections, Humans, Liver Cirrhosis, Liver Transplantation, Male, Middle Aged, Prospective Studies, United Kingdom
Abstract

This study assessed the likelihood of referral for liver transplantation assessment in a prospective cohort of patients co-infected with HIV and hepatitis B or C with complications of cirrhosis. There were 141 co-infected patients from 11 UK centres with at least one complication of cirrhosis recorded (either decompensation or hepatocellular carcinoma) out of 772 identified with cirrhosis and/or HCC. Only 23 of these 141 (16.3%) were referred for liver transplantation assessment, even though referral is recommended for co-infected patients after the first decompensation episode.

DOI10.1007/s15010-016-0976-x
Alternate JournalInfection
PubMed ID28054251
PubMed Central IDPMC5374166
Grant ListMR/M004236/1 / / Medical Research Council / United Kingdom